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Inventi Impact: Ophthalmology

Articles

  • Inventi:hvs/32/12
    COMPARISON OF NEWLY DIAGNOSED OCULAR HYPERTENSION AND OPEN-ANGLE GLAUCOMA: OCULAR VARIABLES, RISK FACTORS, AND DISEASE SEVERITY
    30-Jun-2012 Research 2012 : July - September
    Yvonne M Buys, Paul Harasymowycz, Rania Gaspo, Kenneth Kwok,\r\nCindy M L Hutnik, Pierre Blondeau, Catherine M Birt, Robert L G Piemontesi,\r\nLisa F Gould, Mark R Lesk, Iqbal K Ahmed

    Purpose. To describe the distribution of ocular variables, risk factors, and disease severity in newly diagnosed ocular hypertension\r\n(OH) or open-angle glaucoma (OAG). Methods. Eligible subjects underwent a complete history and examination. Adjusted odds\r\nratios (ORs) and 95% confidence intervals (CIs) obtained from multiple logistic regression models were used to compare OAG\r\nto OH and advanced to early/moderate OAG. Results. 405 subjects were enrolled: 292 (72.1%) with OAG and 113 (27.9%) with\r\nOH. 51.7% had early, 27.1% moderate, and 20.9% advanced OAG. The OR for OAG versus OH was 8.19 (P < 0.0001) for disc\r\nnotch, 5.36 (P < 0.0001) for abnormal visual field, 1.45 (P = 0.001) for worsening mean deviation, 1.91 (P < 0.0001) for increased\r\ncupping, 1.03 for increased age (P = 0.030), and 0.36 (P = 0.010) for smoking. Conclusions. Increased age was a risk for OAG,\r\nand smoking decreased the risk of OAG compared to OH. Almost half of the OAG subjects had moderate/advanced disease at\r\ndiagnosis.

    How to Cite this Article
    CC Compliant Citation: Yvonne M. Buys, Paul Harasymowycz, Rania Gaspo, et al., â??Comparison of Newly Diagnosed Ocular Hypertension\r\nand Open-Angle Glaucoma: Ocular Variables, Risk Factors, and Disease Severity,â? Journal of Ophthalmology, vol. 2012, Article ID\r\n757106, 9 pages, 2012. doi:10.1155/2012/757106.
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